I use all high quality beads.
I personally make myself a set n wear it fr around a month to make sure the beads stand up to every day wear.
Some of the colored skulls do have some color transfer in the beginning but it doesn't last forever.
You can wash them with water and a mild soap if need be.
I do take them off when I shower or swim etc.
Majority of them are glass so if you're gonna do anything extreme probably take them off then too.
Just use your best judgment and if you have any questions feel free to send me a message.